University Staff

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Dr. K.Y. TSE (謝嘉瑜醫生)

Clinical Associate Professor
MBBS; MMedSc; FRCOG; FHKCOG; FHKAM (O&G); Cert RCOG (Gyn Oncology)
  • location
    6/F, Professorial Block, Queen Mary Hospital
  • telephone
    (852) 2255 4518
  • facsimile
    (852) 2855 0947
  • HKU Scholars Hub
Research Interests
  • Gynaecological cancer biology, novel treatment in recurrent / advanced gynaecological malignancies


  • Tang K.S., Yue P.Y.K., Ip P.C.P., Huang R.L., Lai H.C., Cheung A.N.Y., Tse K.Y., Ngan H.Y.S. and Wong A.S.T., Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface, Nature Communications. 2018, 9: 2270. (Publication No. : 285801)

  • Tse K.Y., Chiu W.H.K., Chan K.K.L., Chu M.Y.M., Ngu S.F., Cheung A.N.Y., Ngan H.Y.S. and Ip P.C.P., A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors, American Journal of Clinical Pathology. 2018. (Publication No. : 285802)

  • Liu S., Chan K.K.L., Chu K.H., Wei N., Lau S.K., Ngu S.F., Chu M.Y.M., Tse K.Y., Ip P.C.P., Ng E.K.O., Cheung A.N.Y. and Ngan H.Y.S., Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer, 2018. No. : 294143)

  • Chan K.K., Wong G.W., Wong E.S.Y., Chan K.K.L., Ip P.C.P., Tse K.Y. and Cheung A.N.Y., Impact of iASPP on chemoresistance through PLK1 and autophagy in ovarian clear cell carcinoma, International Journal of Cancer. 2018. (Publication No. : 285798)

  • VYT Cheung, KY Tse. Vulval hemangioma. Journal of Obstetrics and Gynaecology Canada. 2017 May 4. pii: S1701-2163(17)30074-9. doi: 10.1016/j.jogc.2017.02.004.

  • SF Ngu, N Wei, TTC Kwan, MMY Chu, KY Tse, KKL Chan, HYS Ngan. Impact of different educational interventions on psychosocial wellbeing of Hong Kong Chinese women with a positive high-risk human papillomavirus and normal cervical cytology. Journal of Psychosomatic Obstetrics & Gynecology 2017: 10: 1 – 10.

  • KY Tse, HYS Ngan, PC Lim. Robot-assisted gynaecological cancer surgery – complications and prevention. Best Pract Res Clin Obstet Gynaecol 2017 Apr 23. pii: S1521-6934(17)30063-9. doi: 10.1016/j.bpobgyn.2017.04.005. [Epub ahead of print]

  • KL Chow, KY Tse, CL Cheung, KW Wong, ANY Cheung, RWC Wong, ANH Chan, NWF Yuen, HYS Ngan, PPC Ip. The mitosis-specific marker phosphohistone-H3 (PHH3) is an independent prognosticator in uterine smooth muscle tumors: an outcome-based study. Histopathology 2017; 70: 746 - 55

  • KY Tse, VYT Cheung, C Lam, EYP Lee, PL Khong, HYS Ngan. Successful treatment of a para-renal pregnancy using high-dose methotrexate regimen. J Reprod Med 2016; 61: 592 – 94

  • KY Tse. Prevention of cervical cancer – HPV vaccines. Hong Kong Medical Diary 2016; 21 (10): 11 – 5

  • KY Tse, SK Lau, MW Lui, PPC Ip, ANY Cheung, HYS Ngan. Patient compliance with cervical smear surveillance in a shared-care setting. Int J Gyn Obs 2016; 135: 177 - 81

  • Chu MM, Tse KY, Chan KK, Cheung AN, Ngan HY. Placental site trophoblastic tumour – a distinct entity of gestational trophoblastic disease: experience from a tertiary referral center in Hong Kong. J Reprod Med. 2016 Aug;61(4):351-6

  • KY Tse, EPY Lee. Ovarian vein thrombosis in a patient with recurrent ovarian cancer. MIMS Oncology, Dec 2015

  • KY Tse, KKL Chan, KF Tam, HYS Ngan. Current management of gestational trophoblastic disease. Obstetrics, Gynaecology & Reproductive Medicine 2015; 25 (1): 12 – 21

  • EY Lee, ES Hui, KK Chan, KY Tse, WK Kwong, TY Chang, Q Chan, PL Khong. The relationship between intravoxel incoherent motion diffusion-weighted MRI and dynamic contrast-enhanced MRI in tissue perfusion of cervical cancers. J Magn Reson Imaging.  2015; 42: 454 - 9

  • Tse KY and Ngan HYS. The role of laparoscopy in staging of different gynaecological cancers. Best Pract Res Clin Obstet Gynaecol 2015, S1521-6934 (15)00030-9.

  • Chu MM, Ma Y, Tse KY, Chan KK, Ngan HY. Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia. International Journal of Gynecological Cancer 2015 Mar;25(3):498-503.

  • KY Tse, PPC Ip, KKL Chan. Human papillomavirus and cervical cancer. J Paed Obs Gyn 2014; Sep / Oct: 213 – 20

  • KY Tse. Is it a time for universal human papillomavirus vaccination in young women? Hong Kong Medical Diary 2014; 19 (9): 13 – 6

  • Lee EY, Khong PL, Tse KY, Chan KK, Chu MM, Ngan HY. Differentiation of aggressive and indolent subtypes of uterine sarcoma using maximum standardized uptake value. Nucl Med Commun. 2013; 34(12):1185-9.

  • KY Tse, KKL Chan, KF Tam, HY Ngan. Update on gestastional trophoblastic disease. Obstetrics, Gynaecology & Reproductive Medicine 2012; 22: 7 – 15

  • Tse KY, Ngan HY. Gestational trophoblastic disease. Best Pract Res Clin Obstet Gynaecol. 2012 Jun;26(3):357-70. [PubMed]

  • Tse KY, Crawford R, Ngan HY. Staging of uterine sarcomas. Best Pract Res Clin Obstet Gynaecol. 2011 Dec;25(6):733-49. 

  • PP Ip, KY Tse, KF Tam. Uterine smooth muscle tumors other than the ordinary leiomyomas and leiomyosarcomas: a review of selected variants with emphasis on recent advances and unusual morphology that may cause concern for malignancy. Adv Anat Pathol 2010; 17: 91 - 112

  • KY Tse, VW Liu, DW Chan, PM Chiu, KF Tam, KK Chan, XY Liao, Cheung AN, HY Ngan. Epigenetic alteration of the Metallothionein 1E gene in human endometrial carcinomas. Tumour Biol 2009; 30: 93 - 99

  • KY Tse, KKL Chan, KF Tam, Ngan HY. Gestational trophoblastic disease. Obstetrics, Gynaecology & Reproductive Medicine 2009; 19: 89 – 97

  • KK Chan, KF Tam, KY Tse, Ngan HY. The role of regular physical examination in the detection of ovarian cancer recurrence. Gynecol Oncol 2008; 110; 158 – 61

Research Grants
  • Hospital Authority Training Research Assistance Scheme grant for the study of Epigenetic Alteration of the Metallothionein 1E Gene in Human Endometrial Carcinomas
Professional activities
  • Oct 11 – present
    Member of Colposcopy sub-committee, the Hong Kong College of Obstetrics and Gynaecology
  • Oct 16 – present
    Scientific member of the University of Hong Kong / Hospital Authority Hong Kong West Cluster Institutional Review Board (HKU / HA HKW IRB)
  • Jan 17 – present
    Editorial board member of Hong Kong Medical Journal
  • Jan 17 – present
    Treasurer, the Hong Kong Society of Colposcopy and Cervical Pathology
  • Jun 17 – present
    Council member, the Obstetrical and Gynaecological Society of Hong Kong
  • Jan 18 – present
    Member of Gynaecological Oncology sub-committee, the Hong Kong College of Obstetrics and Gynaecology
Awards and Honors
  • 2009
    Hong Kong West Cluster and Queen Mary Hospital Outstanding Teams Award 2009 for “Gynae-Oncology Team, QMH”
  • 2010
    Ho Hung Chiu scholarship for overseas training
  • 2013
    HA Corporate Scholarship Program for Doctors 2014/15 (Robotic Assisted Laparoscopic Surgery in Gynaecological Oncology)
  • 2015
    S S Ratnam - Young Gynaecologist Award (Asian and Oceania Federation of Obstetrics and Gynaecology)
  • 2018
    Hong Kong West Cluster and Queen Mary Hospital Outstanding Teams Award 2018 for “Gynae-Oncology Team, QMH”